Salivary Biomarkers for Oral cancer in Lichen Planus Patients

• Are you an individual with oral lichen planus who has developed mouth cancer?
• If so, you may be eligible for a research study!

What is the purpose of the study?

This NIH-funded study is to explore the possibility of using saliva in an early cancer detection method for lichen planus patients who are known to be at high risk for developing mouth (oral) cancer.

We will need to collect saliva samples from those who have lichen planus then developed oral cancer. Analysis of the saliva samples for several particular proteins and chemicals will be performed. The results will be compared to those who have lichen planus without oral cancer development and to a group of normal controls (people who have neither oral cancer nor lichen planus).

What do I need to do if I participate in this study?

We will need to collect saliva samples once from each eligible patient between 8am and 12pm. You will be asked to refrain from eating, drinking or using oral hygiene procedures. You will be given a water mouthrinse before saliva sample collection. Five minutes after the oral rinse, you will be asked to spit into a 50ml tube. Approximately 8 ml of saliva will be collected within 30 minutes after the start time.

What benefit will I get by participating this study?

You will be compensated by $30 for your participation in this study. You will know that you have made an extremely valuable contribution to science, one that may help save lives and prevent much suffering.

Whom should I call if I am interested in participating in this study?