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Brendan Wong

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Brendan Wong, Ph.D.

Associate Professor
Department of Biomedical Sciences
Member of the GSBS Faculty

3302 Gaston Ave.
Dallas, Texas 75246
Phone: 214-828-8323
Fax: 214-874-4538
Email: bwong@bcd.tamhsc.edu

Education and Post-Graduate Training

Ph.D., Interdisciplinary Physiology, Physics and Chemistry, Southern Illinois University, Carbondale, IL  (1978)

M.A., Department of Physics, Southern Illinois University, Carbondale, IL (1974)

B.S., Department of Physics, University of San Francisco, CA (1971)

Career History

Associate Professor, Department of Biomedical Sciences, Texas A&M Health Science Center Baylor College of Dentistry (1992-present)

Graduate Faculty, Department of Biomedical Sciences, Texas A&M Health Science Center Baylor College of Dentistry (1996-present)

Associate Professor, Department of Physiology, Baylor College of Dentistry (1987-1992)

Assistant Professor, Department of Physiology, Baylor College of Dentisry (1983-1987)

Teaching Interests

Teaching responsibilities include:

Dental Physiology (Course Director), Dental Neuroscience (dental), Integrated Biomedical Sciences (dental hygiene), Applied Medical Physiology (graduate)

Research Interests

  • Effects of estrogen on temporomandibular dysfunction and neuronal excitability.
  • Intracellular Ca2+ imaging with fluorescent dyes and laser scanning confocal microscopy. 
  • Voltageclamp and patchclamp studies on the properties and modulation of ion channels in excitable and nonexcitable membranes, e.g., dissociated gastric smooth muscle cells, dissociated calvarial osteoblasts, and the pheochromocytoma clonal cell line (PC-12). 
  • The effects of general anesthetic agents on cytoplasmic calcium signalling using fluorescent calcium indicator dyes.

Selected Publications

  1. Wong BS. (1991) Ionic conductances in dissociated smooth muscle cells. Proc. Soc. Exp. Biol. Med. 197:125-134.
  2. Wong BS, Martin CD. (1993) Ketamine inhibition of cytoplasmic calcium signalling in rat pheochromocytoma (PC-12) cells. Life Sci./Pharmacol. Lett.  53:PL359-PL364.
  3. McMahon A, Wong BS, Iacopino AM, Ng MC, Chi S, German DC.  (1998)  Calbindin-D28k buffers intracellular calcium and promotes resistance to degeneration in PC12 cells. Mol. Brain Res. 54:56-63.
  4. Ng, MC, Harper RP, Le CT, Wong BS.  (1999)  Effects of estrogen on the condylar cartilage  of the rat mandible in organ culture. J. Oral Maxillofac. Surg.  57:818-823.
  5. Talwar, RM, Wong BS, Svoboda, K, Harper, RP.  (2006)  Effects of estrogen on chrondrocyte proliferation and collagen synthesis in skeletally mature articular cartilage. J. Oral Maxillofac. Surg.  64:600-609.