Postdoctoral Fellowship, Craniofacial Biology, University of Michigan, Ann Arbor, MI (1981-1984)
Ph.D., Anatomy, University of Chicago, Chicago, IL (1980)
B.A., Anthropology, University of Pennsylvania, Philadelphia, PA (1975)
Chair, Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry (2012-present)
Professor, Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry (2004-present)
Director, Graduate Program, Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry (1996-2009)
Associate Professor, Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry (1996-2004)
Graduate Faculty, Texas A&M Health Science Center (1996-present)
Associate Professor, Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry (1993-1996)
Associate Professor, Graduate Faculty, Baylor University (1993-1996)
Assistant Professor, Department of Biomedical Sciences, Baylor College of Dentistry (1992-1993)
Assistant Professor, Graduate Faculty, Baylor University (1987-1993)
Assistant Professor, Department of Anatomy, Baylor College of Dentistry (1986-1992)
Adjunct Assistant Research Scientist, Center for Human Growth and Development, The University of Michigan (1986-1989)
Consultant, Department of Orthodontics, The University of Michigan (1986-1989)
Assistant Research Scientist, Center for Human Growth and Development, The University of Michigan (1984-1985)
Adjunct Assistant Research Scientist, Department of Orthodontics, The University of Michigan (1985)
Lecturer, Department of Anatomy and Cell Biology, The University of Michigan (1984-1985)
Instructor, Department of Anatomy and Cell Biology, The University of Michigan (1980)
Teaching Associate, Department of Anatomy, University of Illinois Medical Center (1979-1980)
Teaching responsibilities include:
Evidence-based Dentistry and Clinical Research (director, dental), Gross Anatomy (graduate and dental), Cell and Molecular Biology of Oral and Craniofacial Tissues, Craniofacial Growth and Development, Biology of Bone and Mineralized Tissues, Function and Evolution of the Craniofacial Region, Bone and Craniofacial Biology Journal Club (director), Scientific Ethics (director, graduate and undergraduate).
Dr. Dechow's research is broadly concerned with the growth, adaptation, and evolution of the craniofacial skeleton and related soft tissues. Throughout his career, he has addressed this area through a variety of biomechanical, material, and morphologic approaches. Early work focused on comparative and morphometric studies of craniofacial form and physiological studies of the muscles of mastication. Specifically, this work concerned the morphology, function, and biomechanics of the masticatory muscles, and the adaptation of the muscles to clinically relevant alterations, such as surgical overloading, detachment, and chronic lengthening. Of particular interest were the relationships between force and speed of masticatory muscles, muscle form, craniofacial growth, and biomechanics.
Later and continuing research includes studies of the structural properties, biomechanics, and modeling of the craniofacial skeleton. This work concerns the understanding of the mechanical and elastic properties of bone in the craniofacial region, and the relationship of variations in the properties to the biomechanics of orofacial form and function. The broad question is how do cellular mechanisms of bone growth and remodeling relate to gross skeletal form, function, and evolution.
Recent research, funded by NIH, is focusing on the functional results of surgical and traumatic insults on the basic structures and function of the craniofacial skeleton, and the impact of alteration, such as distraction osteogenesis, bond plating (stress shielding), osteoporosis, or edentulation, on the craniofacial skeleton.
The diversity of bone tissue in the craniofacial region makes this an optimal area for exploring the relationship between the microarchitecture of cortical bone and its material properties. These later studies have led to the use of ultrasound, confocal microscopy, 3D computer reconstruction of internal tissue organization, and biomechanical modeling, including finite element analysis, as experimental techniques.
A primary interest is the evolution of craniofacial form in humans and other primates. These include the comparative biomechanics, growth, and form of the craniofacial region in both extant and fossil primates, and the relationships between variations in craniofacial structure and function throughout the vertebrates. A major ongoing collaborative project, funded by NSF, is exploring craniofacial structure and feeding mechanics during hominid evolution using advanced techniques of mechanical modeling, structural tissue analysis, and morphological reconstruction of paleontological specimens.
Dr. Dechow belongs to a number of professional organizations, including the American Association of Anatomists, American Association for the Advancement of Science, American Dental Education Association, American Association of Physical Anthropologists, American Society of Biomechanics, American Society for Bone and Mineral Research, American Society of Mechanical Engineers, Human Biology Council, International Association for Dental Research, International Bone and Mineral Society, International Primatological Society, International Society of Musculoskeletal and Neuronal Interactions, Microscopy Society of America, Sigma XI, Society for Clinical Trials, Society for Integrative and Comparative Biology, Society of Vertebrate Paleontology. He has served on a number of committees and held offices (most recently, President of the Craniofacial Biology Group) of the International Association for Dental Research.
Integrative analysis of hominid feeding biomechanics. NSF/Biological Anthropology; 2007-2013. (PI)
CUSPID: Baylor's Oral Health Research Education Grant. NIH R25 DE01883-01; 2008-2013. (Director of dental curriculum revision)
Baylor's Scientific Training Program for Dental Academic Researchers: B-STARS. NIH T32 DE018380; 2008-2013. (Co-I)
Baylor's Program in Bioengineering Sciences and Translational Research (B-BEST). NIH/NIDCR 1 P30 DE020742-01; 2009-2013. (Co-I)
North and Central Texas Clinical and Translational Science Initiative. NIH U54; 2007-2013. (Operations Committee member and mentor)
Evaluation of the mandible bone phenotype of gene-altered animals and/or the effects of novel bone active compounds in animal models. Amgen; 2009-2012. (Co-I)
Scanco VivaCT 40 high speed micro computed tomography system.NIH; 2008-2010.
Sun Y, Jiang Y, Liu Q, Gao T, Feng JQ, Dechow P, D'Souza RN, Qin C, Liu X. Biomimetic engineering of nanofibrous gelatin scaffolds with noncollagenous proteins for enhanced bone regeneration. Tissue Eng Part A 2013, Apr. 5 [Epub ahead of print].
Jin Z, Wei W, Dechow PC, Wan Y. HDAC7 inhibits osteoclastogenesis by reversing RANKL-triggered β-catenin switch. Mol Endocrinol 27: 325-335 [Epub Nov 30, 2012].
Strait DS, Constantino P, Lucas PW, Richmond BG, Spencer MA, Dechow PC, Ross CF, Grosse IR, Wright BW, Wood BA, Weber GW, Wang Q, Byron C, Slice DE, Chalk J, Smith AL, Smith LC, Wood S, Berthaume M, Benazzi S, Dzialo C, Tamvada K, Ledogar JA. Viewpoints: Diet and dietary adaptations in early hominins: The hard food perspective. Am J Phys Anthropol 151:339-355, 2013.
Kontogiorgos E, Elsalanty ME, Zakhary I, Nagy WW, Dechow PC, Opperman LA. Osseointegration of dental implants placed into canine mandibular bone regenerated by bone transport distraction osteogenesis. Int J Oral Maxillofac Implants 28: 677-686, 2013.
Massey CC, Kontogiorgos E, Taylor R, Opperman L, Dechow P, Buschang PH. Effect of force on alveolar bone surrounding miniscrew implants: A 3-dimensional microcomputed tomography study. Am J Orthod Dentofacial Orthop 142:32-44, 2012.
Shibazaki-Yorozuya R, Wang Q, Dechow PC, Maki K, Opperman LA. Changes in biomechanical strain and morphology of rat calvarial sutures and bone after Tgf-β3 inhibition of posterior interfrontal suture fusion. Anat Rec 295:928-938, 2012.
Hobin JA, Deschamps AM, Bockman R, Cohen S, Dechow P, Eng C, Galey W, Morris M, Prabhakar S, Raj U, Rubenstein P, Smith JA, Stover P, Sung N, Talman W, Galbraith R. Engaging basic scientists in translational research: Identifying opportunities, overcoming obstacles. J Transl Med 10:72, 2012.
Berthaume MA, Dechow PC, Iriarte-Diaz J, Ross CF, Strait DS, Wang Q, Grosse IR. Probabilistic finite element analysis of a craniofacial finite element model. J Theor Biol 300:242-253, 2012.
Strait DS, Weber GW, Constantino P, Lucas PW, Richmond BG, Spencer MA, Dechow PC, Ross CF, Grosse IR, Wright BW, Wood BA, Wang Q, Byron C, Slice DE. Microwear, mechanics and the feeding adaptations of Australopithecus africanus. J Hum Evol 62:165-168, 2012.
Wei W, Zeve D, Suh J, Wang X, Du Y, Zerwekh J, Dechow P, Graff J, Wan Y. Biphasic and dosage-dependent regulation of osteoclastogenesis by β-Catenin. Mol Cell Biol 31:4706-19, 2011.
Han X, Liu M, Voisey A, Ren Y, Kurimoto P, Gao T, Tefera L, Dechow P, Ke H, Feng J. Postnatal effect of overexpressed DKK1 on mandibular molar formation. J Dent Res 90:1312-17, 2011.
Zapata U, Halvachs E, Dechow P, Elsalanty M, Opperman L. Architecture and microstructure of cortical bone in reconstructed canine mandibles after bone transport distraction osteogenesis. Calcif Tiss Inter 89:379-88, 2011.
Zapata U, Opperman L, Kontogiorgos E, Elsalanty M, Dechow P. Biomechanical characteristics of regenerated cortical bone in the canine mandible. J Tiss Eng Reg Med 5:551-559, 2011.
Wei W, Zeve D, Wang X, Du Y, Tang W, Dechow P, Graff J, Wan Y. Osteoclast progenitors reside in the peroxisome proliferator-activated receptor gamma-expressing bone marrow cell population. Mol Cell Biol 31:4692-4705, 2011.
Spencer A, Campbell P, Dechow P, Ellis M, Buschang P. How does the rate of dentoalveolar distraction affect the bone regenerate produced? Am J Ortho and Dentofacial Ortho 140:211-221, 2011.
Moore C, Campbell P, Dechow P, Ellis M, Buschang P. Effects of latency on the quality and quantity of bone produced by dentoalveolar distraction osteogenesis. Am J Ortho and Dentofacial Ortho 140:470-478, 2011.
Kontogiorgos E, Elsalanty ME, Zapata U, Zakhary I, Nagy W, Dechow P, Opperman L. Three-dimensional evaluation of mandibular bone regenerated by bone transport distraction osteogenesis. Calcified Tissue International 89: 43-52, 2011.
Chalk J, Richmond BG, Ross CF, Strait DS, Wright BW, Spencer MA, Wang Q, Dechow PC. A finite element analysis of masticatory stress hypotheses. Am J Phys Anthropol 145:1-10, 2011.
Jones DL, Hinton RJ, Dechow PC, Abdellatif H, McCann AL, Schneiderman ED, D'Souza R. The evidence-based dentistry initiative at Baylor College of Dentistry. Tex Dent J 128:177-180, 2011.
Abdellatif H, Dechow PC, Jones DL. Principles of evidence-based dental practice (EBDP). Tex Dent J 128:155-164, 2011.
Hinton RJ, Dechow PC, Abdellatif H, Jones DL, McCann AL, Schneiderman ED, D'Souza R. Creating an evidence-based dentistry culture at Baylor College of Dentistry: The winds of change. J Dent Educ 75:279-290, 2011.
Ross CF, Berthaume MA, Dechow PC, Iriarte-Diaz J, Porro LB, Richmond BG, Spencer M, Strait D. In vivo bone strain and finite-element modeling of the craniofacial haft in catarrhine primates. J Anat 218:112-141, 2011.
Chung DH, Dechow PC. Elastic anisotropy and off-axis ultrasonic velocity distribution in human cortical bone. J Anat 218:26-39, 2011.
Muhney KA, Dechow PC. Patients' perception of pain during ultrasonic debridement: A comparison between piezoelectric and magnetostrictive scalers. J Dent Hyg 84: 185-189, 2010.
Wei W, Wang X, Yang M, Smith LC, Dechow PC, Wan Y. PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss. Cell Metab 11:503-516, 2010.
Foley CH, Kerns DG, Hallmon WW, Rivera-Hidalgo F, Nelson CJ, Spears R, Dechow PC, Opperman LA. Effect of phosphate treatment of acid-etched implants on mineral apposition rates near implants in a dog model. Int J Oral Maxillofac Implants 25:278-286, 2010.
Dechow PC, Wang Q, Peterson J. Edentulation alters material properties of cortical bone in the human craniofacial skeleton: Functional implications for craniofacial structure in primate evolution. Anat Rec 293:618-629, 2010.
Strait DS, Grosse IR, Dechow PC, Smith AL, Wang Q, Weber GW, Neubauer S, Slice DE, Chalk J, Richmond BG, Lucas PW, Spencer MA, Schrein C, Wright BW, Byron C, Ross CF. The structural rigidity of the cranium of Australopithecus africanus: Implication for diet, dietary adaptations, and the allometry of feeding biomechanics. Anat Rec 293:583-593, 2010.
Gluhak-Heinrich J, Guo D, Yang W, Harris MA, Lichtler A, Kream B, Zhang J, Feng JQ, Smith LC, Dechow P, Harris SE. New roles and mechanism of action of BMP4 in postnatal tooth cytodifferentiation. Bone 46:1533-45, 2010.
Pickard MB, Dechow P, Rossouw PE, Buschang PH. Effects of miniscrew orientation on implant stability and resistance to failure. Am J Orthod Dentofacial Orthop 137:91-99, 2010.
Zapata U, Elsalanty ME, Dechow PC, Opperman LA. Biomechanical configurations of mandibular transport distraction osteogenesis devices. Tissue Eng Part B 16:273-283, 2010.
Wang Q, Ashley DW, Dechow PC. Regional, ontogenetic, and sex-related variations in elastic properties of cortical bone in baboon mandibles. Am J Phys Anthropol 141:526-49, 2010.
Zapata U, Metzger K, Wang Q, Elsey RM, Ross CF, Dechow PC. Material properties of mandibular cortical bone in the American allingator, Alligator mississippiensis. Bone 46:860-867, 2010.
Strait DS, Weber GW, Neubauer S, Chalk J, Richmond BG, Lucas PW, Spencer MA, Schrein C, Dechow PC, Ross CF, Grosse IR, Wright BW, Constantino P, Wood BA, Lawn B, Hylander WL, Wang Q, Byron C, Slice DE, Smith AL. The feeding biomechanics and dietary ecology of Australopithecus africanus. Proc Natl Acad Sci USA 106:2124-9, 2009.
Dechow PC, Chung DH, Bolouri M. Relationship between three-dimensional microstructure and elastic properties of cortical bone in the human mandible and femur. In: Vinyard CJ, Ravosa MJ and Wall CE, eds., Primate Craniofacial Function and Biology; Springer: New York, 2008.
Wang Q, Dechow PC, Wright BW, Ross CF, Strait DS, Richmond BG, Spencer MA. Surface strain on bone and sutures in a monkey facial skeleton: An in vitro method and its relevance to Finite Element Analysis. In: Vinyard CJ, Ravosa MJ and Wall CE, eds., Primate Craniofacial Function and Biology; Springer: New York, 2008.
Strait DS, Wright B, Richmond BG, Ross CF, Dechow PC, Spencer MA, Wang Q. Craniofacial strain patterns during premolar loading: Implications for human evolution. In: Vinyard CJ, Ravosa MJ and Wall CE, eds., Primate Craniofacial Function and Biology; Springer: New York, 2008.
Naidu A, Dechow PC, Spears R, Wright JM, Kessler HP, Opperman LA. The effects of bisphosphonates on osteoblasts in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:5-13, 2008.
Wang Q, Dechow PC, Hens SM. Ontogeny and diachronic changes in sexual dimorphism in the craniofacial skeleton of rhesus macaques from Cayo Santiago, Puerto Rico. J Hum Evol 53:350-61, 2007.
Shibazaki R, Dechow PC, Maki K, Opperman LA. Biomechanical strain and morphologic changes with age in rat calvarial bone and sutures. Plast Reconstr Surg 119:2167-2181, 2007.
Strait DS, Richmond BG, Spencer MA, Ross CF, Dechow PC, Wood BA. Masticatory biomechanics and its relevance to early hominid phylogeny: An examination of palate thickness using finite element analysis. J Hum Evol 52:585-599, 2007.
Wang Q, Strait DS, Dechow PC. A comparison of cortical elastic properties in the craniofacial skeletons of three primate species and its relevance to the study of human evolution. J Hum Evol 51:375-382, 2006.
Ross CF, Patel BA, Slice DE, Strait D, Dechow PC, Richmond B, Spencer M. Modeling masticatory muscle force in finite-element analysis: Sensitivity analysis using principal coordinates analysis. Anatomical Record 283A:288-299, 2005.
Strait D, Wang Q, Dechow PC, Ross CF, Richmond B, Spencer M, Patel BA. Modeling elastic properties in finite element analysis: How much precision is needed to produce an accurate model? Anatomical Record 283A:275-287, 2005.
Peterson J, Dechow PD. Material properties of the inner and outer cortical tables of the human parietal bone.Anatomical Record 268:7-15, 2002.
Delson E, Terranova CJ, Jungers WL, Sargis EG, Jablonski NG, Dechow PC. Body mass in Cercopithecidae (Primates, Mammalis): Estimation and scaling in extinct and extant taxa. American Museum of Natural History Novitatas, 2001.